Indianapolis Times, Indianapolis, Marion County, 24 October 1948 — Page 36

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* 0 Scientist Hunting Cause Of Cancer

Basic Problems of Growth Under Study

~ A young Italian-born scientist at Indiana University is on the trail of the thing that may cause " gancer. He is Dr. Salvador E. Luria, + associate professor of bacteri1 \ ology. Through the sub - microscopic world of viruses, the smallest living things yet discovered, he Is seeking a cause of cancer in a ¥ research project Da ® for the AmerJE 4 ican Cancer SoBe 8 ciety. Dr. Luria de-

. : ¥ bl . L Dr. Luria scribed his in-

vestigation to The Times in his éampus laboratory. There were some photos on the wall, “That's the virus.” He Indicated photos of bent ovals of protoplasm. Beside them hung a picture of an attractive woman. “That one’s my wife,” he sald a little absently.

We Don't Know Much

“You know, we can't fight cancer on the basis of what we “know,” he said. “We don't know “much. We have to find out what C7 enncer is; the-genetie-reason body

ro {

A RE SE

. “One way of attacking the ay problem is to understand the EEE RRR RR DORE

. From this point of departure, Dr. Luria is studying the growth of a race of viruses called .bacteria-eaters, ’ He has the organism trapped in culture jars. . The bacteria-eaters are too small to be seen by any device less powerful than the electronmicroscope. Dr. Luria studies it statistically, by its effects on the bacteria on which it feeds.

Is'Mutation, Key?

Some viruses cause cancer in birds. Do they cause cancer in man? Some viruses attack cells. Does that cause some forms of cancer? - Viruses change their characte! istics by mutation. Does mutatiofi hold the key to what happens in the human body “cell when it goes berserk as it does in cancer?

“Pr. Luria and his research team are trying to answer. The team 4neludes Dr. R. Dubecco, research “associate; Mrs. Mary Human, _bacteriologist; Mrs. Joan Headdy, research assistant, and James “ Watson, graduate student. .

wth, the five researchers have observing’ the bacteria-eat-‘er behave for two years. They “wateh it mutate, feed and per- _ form some rather complicated op-

“‘They do this by watching what

bacteria. As the virus feeds, it + makes round holes in the culture. The holes are visible to the naked eye. The size of the hole _ indicates whether the .virus has undergone a mutation. Find ‘Resurrection’ They have observed a curious kind of resurrection in viruses apparently killed by exposure to ultra - violet radiation, Such viruses given radiation treatment ceased to multiply in the bacteria culture—unless two or more of them are placed together. When two apparently dead viruses were placed inside the same bacterium, some active and alive viruses came out. “They seem to exchange or transfer between them the parts we have damaged with radiation,” said Dr. Luria. “But it * takes two or more. It looks like an indication of sexual activity « among the virus.” The significance of this, he explained, is that vaccines made with killed viruses should be checked against the possibility that viruses may resurrect themselves and cause trouble,

A Basic Question The apparent ability of viruses to exchange damaged or dead parts and reproduce

cell to cause cancer, Bacteriologists know, he said,

appear when the cancer has developed. Do viruses then , human cells some abnormal * property to create a cancer cell? % ‘This is one of the basic questions ‘ the research project is investigat-

'BACTERIA-EATER — Here is the bacteria-eating virus at work in a culture of bacteria, The holes show what the virus, invisjble under the ordinary microscope, is doing.

MANY USES FOR SOAP Soap, the cleanser, is used in| -==Small Deposit many industrial plants for other An 2 t applica Holds Your Choice.

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is nothing but abnormal iT

These are some of the questions| -

«In probing - the .mystery of

the vjrus does in a culture of

indicates that some exchange may take place between a virus and a body

that some viruses seem to act as an early cause of cancer, but dis-

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State Physicians to Meet

Here for Annual Convention

2000 Doctors Expected to Attend 3-Day Parley at Murat Temple, Oct. 26, 27, 28

Two thousand Hoosier physicians are expected to atterid the 09th annual convention of the Indiana State Medical Association Oct. 26, 27 and 28 in Murat Temple, From registration at 8 a. m. Tuesday to the annual dinner Thursday night, doctors and their wives will find exhibits, talks and dinner to otcupy them during the three-day period. They will hear 22 scientific y papers read by eight Indiana physiclans and 14 from other states, They will see 120 scientific exhibits and booths arranged by technical exhibitors. If they wish, they may attend up to five of the 30 hour-long in-

of Science.

THE INDIANAPOLIS TIMES

rivers to control of the Oriental

State Academy Meets Thursday

Fall Assembly to Hear Research Reports

Sciefitists from every corner of black shale layered in the earth Indiana will meet at Indiana University Thursday through Satur-\from farm wgods is considered

day, to pool their research dis-| the best means of allowing reprocoveries at the annual fall as- duction of native hardwoods, This

sembly of the Indiana Academy,

Research papers range from a history on Indiana's underground'logical sectional meetings, the

‘

SUNDAY, OCT. 24, 1948

fruit moth,

Plants which existed before Columbus discovered America—be-| fore the birth of Christ—before

history began, are the subject

a paper by J. H. Hoskins and A, T. Cross, of the University

sof Cincinnati. | These flora are found in pet:

fied wood in outcroppings

{in Indiana and Kentucky.

{1s the opinion, and topic of

Uyl, of Purdue. :

The total exclusion of livestock

paper to be given by Danlel De-

During the zoological and blo-

riof

Joseph's College, Rensselaer, willlcould be found. give a paper on assorted biological microphotographs.

orchard men care to remember, an annoying and costly plague

to the ‘industry, Until the discovery and application of DDT,

Rev. John W, Baechle, B8t|trolling these devastating insects and fields of Hoosierland, Gayle

| Thornbrough,’ a member of the

But G. Edward Marshall, of|Indiana Historical Society, will

the Purdue Agricultural Expert: For more years than Indiana ment Station, will tell the meet-|early Indian life. ing of how the. periodic spraying| the Oriental fruit moth had been|of infected areas will virtually erase all signs of the insect. {dealing with -Hudelson Cavern, An authority on the traditions, superstitions, and folklore of the uO no state-wide method for con-'Indian who once roamed the hills' Orange » County.

speak on interesting phases of

Clyde A. Malott, of Indiana

University, will offer a paper

and will trace the route of the

“lost river” {in

structional courses to be offered Tuesday. Tiere will be separate| sessions for opthalmologists,| chest specialists, radiologists and general practitioners, { In spite of this apparently full schedule, an entertainment pros gram is planned. Tuesday a golf tournament is scheduled at Broadmoor: Country Club and a trap and skeetshoot at the Indiana Gun Club, A stag party has been arranged Tuesday night. Wednesday there will be special luncheons and class reunions.

Wives to Meet

Attending wives will -not be stranded while their husbands are in session. A theater party is In prospect Tuesday evening. I'rom 2 until 5 p. m. Wednesday Mrs, Ralp Gates Indiana's First Lady, will be hostess at an “Autumn Tea” in the governor's home. Thursday morning, a school of

AMA PRESIDENT—~Dr. Ros: coe L. Sensenich, South Bend, president of the American Med-~ > ical’ Association, will be a quest at the 99th convention of the Indiana State Medical Associa-

tion here. ladies, followed by a bridge lunch- * eon honoring Mrs. Luther H.|of merit will be presented by Dr. Kice, Garden City, N. Y,, presi- Nafe to Dr. Floyd T: Romberger, dent of the Women's Auxiliary 1947 president of the Indiana to the American Medical Associa-| State Medical Association. Dr. tion. : viene, Naf also. will give gold lapel pins i The-entire eorivention group witliand certificates of distinction to . ARNETTE GEE 30 FB TNgrite pi hipty oi phvalolsns ameraberg of fo if “he BgyptiansReom for: thelthe SJ FIfty. Year, Club". dl final banquet, over which Dr.| Dr. Nafe's final action will be LCleon A. Nafe, Indianapolis, as- the Pressatin of an award to TRIS 1 RE hysisian SdRning. the namie boo Dr. Irons té Epeak : or on of ads aa . o of the Year.” Dr. Ernest E. Irons, Chicago, president-elect of the American Medical Association, will be the| t principal speaker at the dinner. REPLY BY LINCOLN His subject is, ‘‘Socialism, Medi-| Abraham Lincoln took time cine and Ecoriomics.” A specialiout from his presidential duties in guest will ‘be Dr. Roscoe L.[1862 to answer an editorial pubSensenich, South Bend, retiring lished by Horace Greeley urging . AMA. president. that Lincoln immediately free the

The convention will [clone at the end of the banquet.

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